在治疗放射性治疗格雷夫斯病后的小囊底狭窄症:一个病例报告
Claire Ettlin1, Roland Giger1, Yves Jaquet1,2
1Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Head & neck
|December 31, 2025
概括
放射性 (RAI) 治疗可能是一种罕见的小结节狭窄症 (SGS),即呼吸道狭窄的罕见原因. 这份案例报告表明RAI和SGS之间存在联系,得到了组织分析的支持,显示了辐射引起的损伤.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
背景情况:
- 喉下狭窄 (subglottic stenosis,SGS) 是一种先天性或获得性气道在喉下狭窄的症状.
- 长时间的输管是获得SGS的最常见原因,但其他原因尚未完全理解.
研究的目的:
- 报告可能由放射性 (RAI) 治疗引起的小肠缩病例.
- 为了调查SGS患者辐射诱导损伤的组织病理学发现.
主要方法:
- 一名37岁的格雷夫斯病患者接受RAI治疗,出现了,听力障碍和咳.
- 通过内镜怀疑SGS的诊断,并通过MRI确认.
- 进行了悬浮微喉镜检查,并进行了活检和扩张.
主要成果:
- 组织病理学揭示了慢性炎症,纤维化和反应性上皮细胞变化,与辐射诱导的损伤一致.
- 患者有一个迈尔 - 棉花等级II SGS.
- 随着内镜扩张,只有轻微的前面突仍然没有复发性狭窄.
结论:
- 这一案例表明RAI治疗与SGS发展之间存在时间关联.
- 组织病理学发现支持辐射诱导的组织损伤是SGS的原因.
- 在没有其他风险因素的情况下,RAI治疗可能是获得SGS的罕见原因.
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