同时的皮肤穿透左心房尾关闭和透气管大动脉植入:在心房中双击组合
Ahmet Kıvrak1, Ahmet Hakan Ateş1, Mert Doğan2
1Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Anatolian journal of cardiology
|December 31, 2025
概括
结合过导管大动脉植入 (TAVI) 与左心房尾关闭 (LAAC) 是心房 (AF) 患有高出血风险的患者的可行选择,避免长期抗凝,并显示出良好的短期安全性.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 患有心房 (AF) 的患者接受过导管大动脉植入 (TAVI),通常需要长期口服抗凝剂 (OAC).
- 对一些患者来说,OAC可能会造成高出血风险.
- 在TAVI期间,左心房尾关闭 (LAAC) 可以在没有长时间抗凝治疗的情况下减轻血栓栓塞的风险.
研究的目的:
- 评估执行同一会话TAVI和LAAC的可行性和安全性.
- 评估这种联合手术在患有高出血风险或对OAC的禁忌的患者的疗效.
主要方法:
- 一个单一中心的研究包括连续5名患有严重大动脉狭窄和AF的患者.
- 患者在2024年10月至2025年3月期间接受了同期TAVI和LAAC.
- 技术成功是由门学术研究联盟-3 (VARC-3) 为TAVI和LAAC的特定标准定义的.
主要成果:
- 所有5名患者 (平均年龄75.6±8.4岁) 均取得了技术上的成功.
- 没有发生程序内并发症,严重出血,中风或血管并发症.
- 一名患者经历了1期急性损伤;中位数住院时间为4天.
结论:
- 同一次的TAVI和LAAC在高出血风险的AF患者中是技术上可行的.
- 联合程序显示了可接受的短期安全概况.
- 需要进行更大规模的前性研究,并进行更长时间的随访.
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