在患有神经omyelitis光学谱障碍患者的冷漠
Zihan He1, Wenjing Li1, Xinyue Huang1
1Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
PloS one
|December 31, 2025
概括
无动于衷影响近一半的神经髓炎光学谱系障碍 (NMOSD) 患者,显著影响他们的生活质量. 抑郁症是关键因素,强调了在NMOSD护理中对冷漠的评估和管理的需要.
科学领域:
- 神经学 神经学
- 神经精神病学是一种神经精神病学.
- 临床心理学 临床心理学
背景情况:
- 漠不关心是神经疾病中常见的一种神经精神问题.
- 它在神经脊髓炎光学谱系障碍 (NMOSD) 中的患病率仍然未被探索.
研究的目的:
- 调查NMOSD患者的冷漠的发生和特征.
- 探索NMOSD中冷漠与各种临床和生活状况因素之间的关系.
主要方法:
- 66名NMOSD患者使用冷漠度评估量表-自我报告 (AES-S) 进行了评估.
- 收集的数据包括人口统计,病史,焦虑,抑郁,疲劳,睡眠质量和整体生活质量.
- 进行了统计分析,以确定相关性和重要因素.
主要成果:
- 40.9%的NMOSD患者表现出临床显著的冷漠 (AES-S评分≥36).
- 漠不关心与较低的教育程度,增加的攻击,更长的疾病持续时间,更高的残疾,更糟糕的焦虑,抑郁,疲劳和睡眠质量.
- 抑郁症成为无动于衷的重要独立预测因素,这对生活质量产生了负面影响.
结论:
- 漠不关心是NMOSD的一个常见并发症,与生活质量下降密切相关.
- 识别和管理冷漠,特别是在抑郁症的背景下,对于改善NMOSD患者的治疗结果至关重要.
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