在战术战斗中使用抗生素伤亡护理2025年:TCCC变更25-1
Piotr Wisniewski1, Yusof A Becker2, Derek T Larson2
12nd Medical Battalion, 2nd Marine Logistics Group, Camp Lejeune, NC.
概括
更新的战术战斗伤亡护理 (TCCC) 准则建议新的抗生素用于战斗伤口. 现在,由于多药耐药性和伤口微生物学的原因,Cefadroxil或Cefhalexin (口服) 和Ceftriaxone (肠道) 现在被优先选择,而不是较旧的药物.
科学领域:
- 军事医学 军事医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 战术战斗伤亡护理 (TCCC) 准则历史上建议抗生素治疗战斗伤口,因为疏散延迟和污染风险.
- 目前的TCCC抗生素推 (口服莫西弗洛克萨,亲肠内埃尔塔胺) 需要重新评估.
- 关于多药性耐药性 (MDR) 的新兴数据和不断变化的战斗伤口微生物学需要更新指导.
研究的目的:
- 重新评估和更新战术战斗伤亡护理 (TCCC) 的抗生素建议.
- 在TCCC指南中考虑当前的抗生素选择,MDR和对抗伤口微生物学.
- 为了解决最佳的抗生素时间,侵入性手术的预防,局部抗生素的使用和特定的药物选择.
主要方法:
- 多学科小组将于2023年召开会议.
- 关于抗生素疗效和耐药性模式的综合文献综述.
- 专家讨论以解决有关TCCC抗生素使用的关键问题.
主要成果:
- 早期使用抗生素仍然至关重要.
- 建议在TCCC环境中的所有侵入性手术中进行抗生素预防.
- 推的口服抗生素:塞法德罗克西尔 (首选) 或塞法莱克辛 (替代).
- 推的亲肠道抗生素:塞夫特里亚克松.
- 目前没有足够的证据支持在TCCC中使用局部抗生素.
结论:
- 更新的TCCC抗生素建议包括塞法德罗西尔/塞法列辛 (口服) 和塞夫特里亚克森 (亲肠道).
- 需要考虑长期伤亡护理 (PCC) 准则,用于更窄谱的抗生素和对特定伤害模式的监测.
- 建议对创伤后内炎,开放骨折和腹部损伤进行持续监测.
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