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Updated: Jan 7, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

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在真正的潜伏CD4+T细胞克隆中,HIV-1的转录是异质的

Cintia Bittar1, Ana Rafaela Teixeira1, Thiago Y Oliveira1,2

  • 1Laboratory of Molecular Immunology, The Rockefeller University , New York, NY, USA.

The Journal of experimental medicine
|December 31, 2025
PubMed
概括

了解CD4+T细胞中潜伏的HIV-1储存体是开发治疗方法的关键. 这项研究描述了潜伏的HIV-1前病毒,揭示了整合部位和低表达,对潜伏逆转剂的反应很温和.

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