印度尼西亚妇女的职业烟草尘埃暴露 (T-CHARM):前性队列研究的议定书
Ancah Caesarina Novi Marchianti1, Athira Nandakumar2, Elvia Rahmi Marga Putri3
1Department of Public Health, Faculty of Medicine, University of Jember, Jember, Indonesia.
JMIR research protocols
|December 31, 2025
概括
这项研究调查了烟草粉尘暴露 (TDE) 对烟草工人的健康影响. T-CHARM队列研究监测了与职业TDE相关的长期健康结果.
科学领域:
- 职业健康 职业健康 职业健康 职业健康
- 环境健康 环境健康
- 流行病学 流行病学
背景情况:
- 烟草消费与各种疾病有关.
- 烟草粉尘暴露 (TDE) 对烟草工人的健康影响仍未得到充分研究.
研究的目的:
- 为了引入健康评估和风险监测 (T-CHARM) 的烟尘队列研究协议.
- 为了前性地评估TDE对烟草加工工人的健康影响.
主要方法:
- 一项前性队列研究,涉及400名烟草加工业的非吸烟女性和一个对照组.
- 评估与尿中丁氨酸水平相关的健康影响 (代谢综合征,血清,器官功能).
- 分析空气质量,化学物质和统计数据分析.
主要成果:
- 到2025年8月招募了120名参与者,还有80人将被招募.
- 目前正在进行实验室分析;基线结果预计到2025年底.
结论:
- 该T-CHARM研究利用了详细的职业,环境和纵向健康数据.
- 该队列将被监测长达20年,以了解慢性TDE影响.
- 为评估职业TDE对健康的长期影响提供了一个强大的框架.
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