交叉连接的g-cyclodextrin金属有机框架用于黑大豆种子外层的安东基安分发:增强储存稳定性,加载行为和机械洞察力
Quanyu Zhang1, Youling Feng1, Hanyu Liu1
1College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.
Food chemistry
|December 31, 2025
概括
黑大豆种子外层的酸 (BBSACN) 是不稳定的,但新的交叉链接的环极金属有机框架 (CLCD-MOF) 系统增强了它们的稳定性. 这项创新改善了BBSACN在光线,热量和储存下的保留,使食品行业受益.
科学领域:
- 食品科学 食品科学 食品科学
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
背景情况:
- 黑大豆种子外衣的安东素 (BBSACN) 具有重要的抗氧化剂和健康益处.
- BBSACN固有的不稳定性限制了它们的实际应用.
- 环氧金属有机框架 (CD-MOF) 用于化合物输送,但在水性环境中与水友成分作斗争.
研究的目的:
- 开发一个交叉链接的CD-MOF (CLCD-MOF) 系统,以提高BBSACN的稳定性.
- 为了改善水友活性化合物的加载和保护.
主要方法:
- 使用二碳酸作为交叉连接剂来创建CLCD-MOFs.
- 使用SEM,FTIR,XRD和TGA进行物理化学表征.
- 进行了分子动力学模拟,以验证封装和相互作用.
主要成果:
- CLCD-MOF系统在水中显示了7天的结构稳定性.
- 在CLCD-MOF中证实了安托西亚宁的成功封装.
- 非共价相互作用 (键,疏水力) 显著改善了对抗光,热和储存的安托西亚宁稳定性.
- 与自由的BBSACN相比,封装的BBSACN在暴露于光线下保持率高达~35%,在储存和加热过程中得到更大的改善.
结论:
- 开发的CLCD-MOF系统有效地提高了BBSACN在各种条件下的稳定性.
- 这种方法为克服与食品工业中稳定活性化合物相关的挑战提供了有希望的解决方案.
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