在接受非心脏手术的患者中术后心房动
Khatere Roozbehi1, Davood Semirani-Nezhad1, Hamidreza Soleimani1
1Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
The American journal of cardiology
|December 31, 2025
概括
非心脏手术后的术后心房动 (POAF) 显著增加了中风和死亡的风险. 早期识别和管理POAF对于改善患者的治疗结果和预防长期心血管事件至关重要.
科学领域:
- 心脏病学 心脏病学
- 外科手术 手术手术
- 公共卫生 公共卫生
背景情况:
- 手术后心房动 (POAF) 影响5-10%的非心脏手术患者.
- 与没有POAF (nPOAF) 相比,POAF的长期心血管影响尚不清楚.
研究的目的:
- 评估非心脏手术后新发性POAF患者心血管结局的发生率.
- 为了比较POAF和nPOAF患者之间的长期风险.
主要方法:
- 在PubMed,EMBASE和Scopus的系统文献搜索.
- 使用随机效应模型对14项研究 (3,622,824名患者) 的聚合分析.
- 时间到事件和受限制的平均生存时间 (RMST) 分析.
主要成果:
- POAF与更高的一年中风风险 (HR 2.34) 和增加住院 (HR 3.29) 和1年死亡率 (HR 1.64) 相关.
- 在POAF患者中,住院或中风的累积发病率更高 (HR 1.75).
- RMST分析显示,POAF患者在15天前就医或中风.
结论:
- 新发性POAF是手术后心血管不良事件的重要危险因素.
- 早期发现和管理POAF是必不可少的.
- 进一步研究包括抗凝药在内的预防策略是有必要的.
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