肺置换相关的变化,在修复的Fallot四分法中的双全球功能指数
Shanique Sterling-Lovy1, Francesca Sperotto1, Lynn A Sleeper1
1Department of Cardiology, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
概括
在肺置换 (PVR) 之前,在Fallot (rTOF) 患者的修复四重症患者中,双全球功能指数 (BVGFI) 通常会降低,并且在PVR后通常保持稳定. 较低的PVR前BVGFI,男性性别和严重的肺吐与PVR后更糟糕的BVGFI有关.
科学领域:
- 心脏病学 心脏病学
- 儿童心脏病学 儿童心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 降低的双心脏全局功能指数 (BVGFI) 与修复的Fallot四分法 (rTOF) 的不良结果有关.
- 肺置换 (PVR) 对rTOF患者BVGFI的影响尚不清楚.
研究的目的:
- 在rTOF患者的PVR后评估BVGFI变化.
- 为了确定与严重抑郁后PVR BVGFI相关的PVR前因素.
主要方法:
- 133名接受PVR的rTOF患者的回顾性队列研究,与心磁共振 (CMR) 影像处理程序前和后.
- 在rTOF患者和对照人群之间比较BVGFI.
- 分析PVR前与PVR后BVGFI相关的PVR前因素.
主要成果:
- 几乎一半的rTOF患者在PVR前有不正常的BVGFI;整体BVGFI在PVR后保持稳定.
- 右心室全局功能指数 (RVGFI) 在PVR后下降.
- 与PVR后严重抑郁的BVGFI相关的因素包括较低的PVR前BVGFI,男性性别,中度/严重的肺吐,以及较高的左心室末缩体积指数.
结论:
- 在PVR前的rTOF患者中,BVGFI经常处于抑郁状态,PVR后通常稳定.
- 在PVR前的BVGFI,男性性别,肺反的严重程度和LVESVi是PVR后BVGFI状态的关键预测因素.
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