在儿童群体的高分辨率直肠计时测量出的体位对排便机制的影响:病例对照研究的方案
Barbara Skowrońska1, Aleksandra Banaszkiewicz2, Marcin Banasiuk2
1The Department of Pediatric Gastroenterology, Medical University of Warsaw, Warsaw, Poland barbara.skowronska@wum.edu.pl.
BMJ open
|December 31, 2025
概括
在儿童进行3D直肠测量时调查身体位置,揭示了不协同排便检测的差异. 坐姿可能为便秘评估提供更准确的评估.
科学领域:
- 胃肠病学 胃肠病学
- 儿科功能性胃肠道疾病
- 诊断成像诊断成像的使用
背景情况:
- 三维高分辨率阳门测量 (3D HRAM) 评估了下胃肠功能,但通常是在非生理位置进行的.
- 当前的协议可能会导致对排便动态的误解,可能会高估异常.
- 不协同排便 (DD) 是便秘的常见原因,需要准确的诊断方法.
研究的目的:
- 为了评估身体位置 (仰卧 vs 坐着) 在儿童排便操作期间对3D HRAM参数的影响.
- 为了比较患有便秘的儿科患者的卧式和坐着姿势的失能性排便 (DD) 检测率.
主要方法:
- 一项前性病例控制研究,涉及5至18岁儿童.
- 两组:功能性便秘/非保留性便失禁 (罗马四标准) 和健康对照组.
- 3D HRAM在仰卧和坐着的位置相继执行,随机顺序.
主要成果:
- 这项研究旨在确定主要终点:坐姿和卧姿之间DD检测率的差异.
- 分析的重点是比较在两个位置的排便尝试期间的测量力参数.
- 结果将阐明姿势对排便生理学评估的影响.
结论:
- 结果将为儿童便秘评估中3DHRAM的最佳定位提供信息.
- 这项研究可能会导致修订协议,以更准确地诊断排便障碍.
- 了解位置效应对于改善3DHRAM在儿童中的临床效用至关重要.
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