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识别可能引发自身免疫性皮肤疾病的免疫刺激性草药补充剂:系统范围审查
Jeffrey D Weiner1,2, Alannah Hill1,2, Catherine Shen1,2
1Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Lupus science & medicine
|December 31, 2025
概括
这项研究确定了227种免疫刺激性草本补充剂,其中15种显示出最有力的证据. 这些草药可能会引发或恶化自身免疫性皮肤疾病,需要临床意识.
科学领域:
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 草药补充剂被广泛用于免疫支持.
- 一些免疫刺激性草药可能会对患有自身免疫性疾病的个体构成风险.
- 自身免疫性皮肤疾病越来越令人担忧,需要了解潜在的触发因素.
研究的目的:
- 系统地识别具有免疫刺激性质的草药补充剂.
- 评估这些补充剂引发或加剧自身免疫性皮肤疾病的潜力.
- 为临床医生提供患者咨询的参考资料.
主要方法:
- 进行了PubMed的系统范围审查.
- 使用特定关键字搜索了草药补充剂对免疫刺激作用的研究.
- 包括体外,模型生物和人类/临床研究.
主要成果:
- 确定了227种不同的免疫刺激草药补充剂.
- 15种草药在所有研究类型中显示出最强有力的证据.
- 这些草药,包括草和阿什瓦甘达,激活炎症通路.
结论:
- 编制了一份包括227种免疫刺激草药的综合清单.
- 由于有强有力的证据,有15种特定的草药需要特别注意.
- 临床医生应向患有自身免疫性皮肤疾病的患者提供有关这些补充剂相关风险的建议.
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