间歇性禁食对脂质概况的影响 - - 一个综合性综述
Joanna Popiolek-Kalisz1, Adrian Kwasny2
1Department of Clinical Dietetics, Medical University of Lublin, ul. Chodzki 7, 20-093, Lublin, Poland; Department of Cardiology, Cardinal Wyszynski Hospital in Lublin, al. Krasnicka 100, 20-718, Lublin, Poland; PoLA Young Lipidologists Committee, Poland.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|December 31, 2025
概括
间歇性禁食 (IF) 对脂质样本显示出适度的益处,特别是降低甘油三 (TG). 时间限制饮食 (TRE) 具有潜力,但需要更多的研究来一致地管理失脂症.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因之一.
- 失脂症是心血管疾病的一个显著可修改的风险因素.
- 包括间歇性禁食 (IF) 在内的饮食干预措施正在探索用于管理脂质障碍.
研究的目的:
- 评估最近对IF对脂质配置文件影响的分析.
- 评估各种IF方案:时间限制饮食 (TRE),交替禁食 (ADF) 和斋月间歇性禁食 (RIF).
- 分析对总胆固醇 (TC),LDL-C,HDL-C和甘油三 (TG) 的影响.
主要方法:
- 在PubMed,Scopus和Web of Science (2020-2025) 中进行系统搜索.
- 包括关于FI和脂质参数的人类研究的元分析.
- 分析了57个符合纳入标准的元分析.
主要成果:
- TRE显示了适度的甘油三降低,特别是在超重个体;对其他脂质的影响有限.
- ADF对脂质资料产生了不一致的影响.
- RIF表示TG和HDL-C的适度改善.
- 研究中的显著异质性限制了最终的结论.
结论:
- 对于脂质配置文件,IF提供了潜在的适度益处,主要是TG降低.
- TRE看起来很有前途,特别是在热量限制方面,但证据尚未确定.
- 异质性和短时间的研究需要通过标准化方案进行进一步的研究.
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