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Updated: Jan 7, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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帕拉的依赖体DNA结合和细胞毒性 (II) 复合物

Francesca Binacchi1, Damiano Cirri1, Tania Gamberi2

  • 1Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy.

Chemistry (Weinheim an der Bergstrasse, Germany)
|December 31, 2025
PubMed
概括

研究人员探索了复合物作为抗癌药物的替代品. 基于Phenanthroline的Palladium复合物显示出对卵巢癌细胞的显著细胞毒性,与Diaminocyclohexane复合物不同.

关键词:
(1R,2R) -1,2 - - 氨酸环素1,10-南林的使用.它们是DNA插曲.帕拉 (Palladium) 的抗癌复合物结构活动关系结构活动关系

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