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在接受口服向治疗的转移性癌症患者的家庭监督炼:AFSOS-Unicancer QUALIOR随机二期研究

Florence Joly¹, Claudia Lefeuvre-Plesse², Emilie Charton³

¹Department of Medical Oncology Centre François Baclesse, CAEN, ; Inserm U1086 "Anticipe" - University Unicaen, CAEN, France.

|December 31, 2025

概括

对于接受口服向治疗的转移性癌症患者来说,在家进行监督的体育炼计划 (SPEP) 是可行的. 这种干预措施有效地减少了与癌症相关的疲劳,并保持了疼痛控制.

科学领域:

在瘤学瘤学.
运动科学运动科学
患者护理患者护理

背景情况:

在 QUALIOR 试验中,对接受口服向治疗的转移性癌症患者进行了家庭监督体育炼计划 (SPEP).
接受口服向治疗的转移性癌症患者往往会经历明显的疲劳和疼痛,影响生活质量.

研究的目的:

对接受口服向治疗的转移性癌症患者进行为期3个月的家庭SPEP的可行性进行评估.
评估SPEP对这种患者群体疲劳和疼痛水平的影响.

主要方法:

一个第二阶段的多中心试验随机分配了112名患者 (2:1) 接受一个为期3个月的家庭SPEP,教练或对照组通过小册子接受适应的体育炼建议.
可行性被定义为患者完成至少50%的计划SPEP会议的比例.
疲劳和疼痛是次要终点,使用视觉模拟量表 (VAS) 进行测量.

主要成果:

在SPEP手臂中的61%的患者完成了至少50%的计划,证明了可行性.
3个月后,SPEP组的中位疲劳得分从4下降到3,持续控制疼痛.
与对照组 (62%,p=0.004) 相比,SPEP手臂的患者在3个月后 (27%) 显示高VAS疲劳率明显较低.

结论:

基于家庭的监督体育炼计划对于接受口服向治疗的转移性癌症患者来说是可行的和有益的.
SPEP可以有效地减轻与癌症相关的疲劳,并保持疼痛控制,改善患者的治疗结果.

关键词:

转移性癌症是一种转移性癌症.在家监督体育炼计划 (SPEP)口服有针对性的治疗方法.

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