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高严重度麻醉相关不良事件的发生率与增加PREDIC³T风险类别在先天性心脏导管:对C3PO数据库的审查

Kristin Chenault¹, Grace R Rahman², Kimberlee Gauvreau²

¹Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.

Paediatric anaesthesia

|January 1, 2026

概括

在儿科心脏导管治疗中,高严重度麻醉相关不良事件 (ARAE) 增加,在先天性心脏导管治疗 (PREDIC3T) 风险类别中,程序风险更高. 患者的低体重和血液动力学脆弱性等因素也会增加风险.

科学领域:

儿科麻醉学儿科麻醉学
遗传性心脏病是一种先天性心脏病.
心脏导管治疗的心脏导管治疗

背景情况:

麻醉对于接受心脏导管治疗的儿科先天性心脏病 (CHD) 患者至关重要.
程序已经从诊断转向复杂的干预,需要麻醉师的专业知识.
与麻醉相关的不良事件 (ARAE) 在这个脆弱人群中是令人担忧的.

研究的目的:

为了确定儿科心脏导管治疗中高严重性ARAE的发生率.
评估ARAE率与先天性心脏导管治疗 (PREDIC3T) 过程风险之间的相关性风险类别.
为了确定与高严重程度的ARAE相关的患者和程序因素.

主要方法:

多中心回顾性队列研究,使用来自先天性心脏导管项目成果 (C3PO) 的前性数据.
分析了来自18个机构的38,021次心脏导管治疗 (2019-2023年).
根据PREDIC3T的风险类别对17个特定的ARAE率的分层.

主要成果:

整体ARAE率为0.8%,高严重性ARAE为0.4%.
高严重性ARAE的发病率与较高的PREDIC3T风险类别 (0.2%至0.8%) 相比增加.
与高度严重的ARAE相关的因素包括体重<10kg,血液动力学脆弱性评分≥1和PREDIC3T类别5程序.

结论:

较高的PREDIC3T风险类别与高严重性ARAE的增加率有关.
患者特异性因素和程序特征都会影响儿科心脏导管治疗中的ARAE.
风险分层工具对于在复杂的儿科心脏手术中管理麻醉安全至关重要.

关键词:

不良事件不良事件不良事件麻醉是一种麻醉.生产性心脏导管治疗的先天性心脏导管.遗传性心脏病是一种先天性心脏病.镇静镇静是一种镇静.

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