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Updated: Aug 13, 2026

A Lab-On-A-Chip Platform for Stimulating Osteocyte Mechanotransduction and Analyzing Functional Outcomes of Bone Remodeling
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通过激活Wnt信号传导,通过Piezo1介导的无脚手架的快速生成自我矿化骨器官

Linxue Zhang1, Yunfan Zhang2, Zhuo Wan1

  • 1Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, China.

Materials today. Bio
|January 1, 2026
PubMed
概括

研究人员开发了一种新的方法,使用Piezo1激活干细胞快速创建无脚手架的自我矿化骨器官 (BO). 这一突破加速了骨再生,为潜在的治疗应用.

关键词:
生物矿物化 生物矿物化骨有机物 骨有机物 骨有机物细胞球形状的球形状.机械生物学 机械生物学这是一个Piezo1.来自人体脱皮叶状牙 (SHED) 的干细胞.

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