在学龄儿童中维生素D缺乏和喘发病率:单中心队列研究
1Department of Pediatrics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Frontiers in public health
|January 1, 2026
概括
在患有喘的儿童中,维生素D缺乏是常见的,与更糟糕的喘控制和更多的恶化有关. 建议进行常规查和补充剂,以更好地治疗儿科喘.
科学领域:
- 儿科肺病学 儿科肺病学
- 营养免疫学 营养免疫学
- 公共卫生 公共卫生
背景情况:
- 喘是全球儿童疾病的重要原因之一.
- 越来越多的人认为维生素D缺乏是免疫调节和呼吸系统健康的一个因素.
- 关于维生素D与控制喘和低收入和中等收入人口儿童喘恶化相关的数据有限.
研究的目的:
- 调查患有喘的学龄儿童中维生素D缺乏症的流行情况.
- 确定维生素D状况与喘控制,恶化频率和住院率之间的关联.
- 确定维生素D缺乏是儿童患者喘控制不良的独立预测因素.
主要方法:
- 对210名被诊断患有喘的儿童 (6-14岁) 进行了回顾性研究.
- 收集的数据包括人口统计,喘控制,恶化,住院和血清维生素D水平.
- 统计分析包括千二测试,ANOVA和多变量逻辑回归.
主要成果:
- 45.2%的儿童患有维生素D缺乏症;31.0%的儿童患有维生素D缺乏症.
- 喘控制不良 (63.2%),喘恶化较高 (2.6/年) 和住院 (31.6%) 在缺陷儿童中明显更常见.
- 维生素D缺乏独立预测了喘控制不良 (aOR:2.8,p < 0.001).
结论:
- 维生素D缺乏在患有喘的儿童中非常普遍,并且与较差的疾病控制和结果有关.
- 在儿科喘护理中应考虑进行常规的维生素D查和补充.
- 专注于营养干预的公共卫生倡议可能会减少儿童的喘负担.
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