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Updated: Jan 7, 2026

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网站特定的蛋白质PEGylation:对结构和功能变化的洞察

Ming Ma1,2, Jinwei Di3, Chengcai Wang1,2

  • 1State Key Laboratory of National Security Specially Needed Medicines, Beijing 100039, China.

Acta pharmaceutica Sinica. B
|January 1, 2026
PubMed
概括

聚乙烯甘醇 (PEG) 修饰通过降低免疫性和延长半衰期来增强蛋白质药物输送. 本综述探讨了PEG蛋白相互作用及其对蛋白质结构,功能和稳定性的影响,以改善药物开发.

关键词:
生物结合的生物结合药物交付是药物交付的过程.纳米医学是一种纳米医学.这种蛋白质是PEGylated蛋白质.聚乙烯甘醇 (PEG) 是一种聚乙烯甘醇.蛋白质构成的结构.蛋白质的功能性 蛋白质的功能性特定地点的PEGylation 化

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