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在荷兰的流行病中断后,儿童RSV感染的季节性和年龄分布的正常化

Neele Rave¹, Marit E M de Bruijne¹, Rebecca K Stellato²

¹Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, Utrecht, The Netherlands.

Open forum infectious diseases

|January 1, 2026

概括

呼吸道同胞性病毒 (RSV) 流行病学受到COVID-19的干扰. 流行后的数据显示,荷兰的RSV季节性和年龄分布已经恢复到典型的流行前模式.

科学领域:

儿科儿科儿科
传染性疾病传染性疾病
流行病学流行病学

背景情况:

COVID-19 流行病显著改变了全球呼吸道同胞性病毒 (RSV) 流行病学.
有限的数据存在RSV趋势在后疫情时代.

研究的目的:

分析荷兰儿童RSV季节性,年龄分布和疾病严重程度的变化.
为了比较COVID-19大流行之前,期间和之后的RSV流行病学.

主要方法:

一项前性监测研究包括2021年5月至2024年4月期间在荷兰47家医院接受RSV治疗的两岁以下儿童.
人口和临床数据与COVID前 (2018-2020),COVID和COVID后 (2022-2024) 期间进行了比较.

主要成果:

在异常的季外转移和特有循环后,RSV的季节性已经恢复到典型的冬季模式.
在2021年夏季爆发期间入院的RSV阳性儿童的中位数年龄比大流行前 (2.2个月) 高 (4.9个月),但在2023/2024年冬季恢复到基线.
在研究期间,在早产或并发症患病率方面没有发现显著差异.

结论:

由于COVID-19大流行,RSV流行病学发生了深刻的破坏.
这项研究表明,荷兰迅速恢复了大流行前的RSV模式,包括年龄分布.

关键词:

流行病学流行病学免疫接种免疫接种免疫接种在COVID-19后的时间里.呼吸道同胞性病毒季节性的季节性.

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