基于便免疫化学测试的结直肠癌查中的风险分层:公众对定制邀请间隔的接受和经验
Brenda J van Stigt1, Elyse E C Rijnders2, Lucie de Jonge1
1Department of Public Health, Erasmus MC University Medical Centre; Rotterdam, the Netherlands.
Preventive medicine reports
|January 1, 2026
概括
参与者接受了基于便中的血红蛋白水平的定制结肠直肠癌查间隔. 对查提供者的信任和明确的沟通是成功实施风险分层查计划的关键.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 查计划 查计划
背景情况:
- 使用便血红蛋白 (f-Hb) 的风险分层可以改善基于便免疫化学测试 (FIT) 的结直肠癌 (CRC) 查.
- 在风险分层的CRC查中接受个性化查间隔仍未得到充分研究.
研究的目的:
- 在一个风险分层的CRC查试验中,探索参与者与量身定制的邀请间隔的经验.
- 根据先前的f-Hb水平,评估不同邀请频率的接受程度.
主要方法:
- 与PERFECT-FIT试验的参与者进行了五个半结构化焦点小组和四个个人采访.
- 根据f-Hb.参与者被分为较短 (一年) 或较长 (三年) 的邀请间隔.
- 使用ATLAS.ti.ti.进行了采访成绩单的主题分析.
主要成果:
- 由于FIT负担较低和早期检测的愿望,参与者更喜欢加强查,随时接受更短的间隔.
- 延长的间隔引起了对遗漏病变的担忧,但由于低风险分类的保证而被接受.
- 对提供者的科学评估的信任使得接受风险分层间隔变得更容易,特别是如果在全国范围内实施.
结论:
- 在基于人群的CRC查中,可接受量身定制的邀请间隔.
- 对查提供者的高度信任对于接受至关重要.
- 清晰的沟通,特别是关于负面FIT结果的沟通,对于过渡到风险分层查至关重要.
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