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Updated: Jan 7, 2026

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与瘤相关的巨细胞的LIPA驱动的重编程在骨髓瘤中形成了免疫抑制的微环境

Zehao Guo1, Yutong Zou1, Yan Liao1

  • 1Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, Guangdong, China.

International immunopharmacology
|January 1, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
利巴公司骨髓瘤一个 TAM三糖代谢瘤微环境

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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