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Updated: Jun 22, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
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对心脏辅助系统的原型离心转子的生物安全评估

Przemysław Kurtyka1,2, Justyna Więcek-Chmielarz2, Marcin Surmiak3,4

  • 1Foundation of Cardiac Surgery Development, Institute of Heart Prosthesis, Zabrze 41-800, Poland.

ACS biomaterials science & engineering
|January 1, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
血液物质的相互作用用于支持心脏的转子立体石刻技术

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Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...