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通过染色体免疫沉分析PD-L1转录活性

Suprataptha U Reddy1, Riddhi Mehta1, Ivana Vancurova2

  • 1Department of Biological Sciences, St. John's University, Queens, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|January 1, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
癌症免疫疗法染色体免疫沉其他:核 PD-L1 的卵巢癌其他类型转录转录法规

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Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
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Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
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