ATF4通过六基因酶II介导的糖解促进管间纤维化
Songtao Feng1,2, Yueming Gao3, Zheng Wang1
1Institute of Urinary System Diseases, Department of Nephrology, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.
Frontiers in immunology
|January 2, 2026
概括
No abstract available in PubMed .
相关概念视频
Acute Kidney Injury II: Pathophysiology
840
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
840
PI3K/mTOR/AKT Signaling Pathway
5.2K
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast, mTORC2 consists of a...
5.2K


