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Updated: May 2, 2026

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
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T细胞大颗粒性淋巴细胞白血病的突变谱:来自AACR项目GENIE联盟的见解

Bhanu Surabi Upadhyayula1, Grace S Saglimbeni2, Edie Gobel3

  • 1School of Biological Sciences, University of California, Davis, CA, U.S.A.

Cancer genomics & proteomics
|January 2, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
美国癌症研究协会 (AACR) 基因组学证据新生病信息交换项目 (GENIE)在FAS其他国家在STAT2T细胞大颗粒性淋巴细胞白血病 (T-LGLL)身体突变

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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
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