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Updated: Jan 7, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
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Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

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与疼痛相关的诱导潜力在多神经病的遗传性转氨化症中

Renan Flávio de França Nunes1, Maria Paula Carvalho Azevedo1, Alberto Rolim Muro Martinez1

  • 1Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.

Muscle & nerve
|January 3, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
唤起的潜力遗传性转氨基酸性多神经病变神经传导研究神经病的疼痛小纤维神经病变

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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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