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Updated: May 6, 2026

Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans
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Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans

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使用Caenorhabditis elegans转录因子RNAi平台进行制阻燃剂的体内高通量毒性查

Siyeol Ahn1, Elizabeth Dufourcq Sekatcheff1, Jinhee Choi1

  • 1School of Environmental Engineering, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul 02504, Republic of Korea.

Toxicology
|January 3, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
不良结果的途径类植物新方法方法 (NAM)RNA干扰 (RNAi) 的情况化阻燃剂

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RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
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Experimental RNAi02:15

Experimental RNAi

RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
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