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ASO视觉摘要:在接受初始不可切割的RAS/RAF突变结直肠癌肝转移局部治疗的患者中,循环瘤DNA的复发和存活的预后价值

Marinde J G Bond1, Karen Bolhuis2, Theodora C Linders3

  • 1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. M.J.G.Bond-2@umcutrecht.nl.

Annals of surgical oncology
|January 4, 2026
PubMed
概括

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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