怀孕前和怀孕期间母亲的,和补充剂摄入量及其与早产风险的关联:基于一项大型队列研究
Zifu Wang1,2, Lei Cao1, Yuqing Li1
1School of Public Health, Gansu University of Chinese Medicine, Lanzhou, 730000, Gansu Province, China.
Journal of health, population, and nutrition
|January 4, 2026
概括
怀孕前和怀孕期间,母亲在怀孕第二个三个月的摄入量和摄入量对于预防早产 (PTB) 至关重要. 增加和补充剂在第三个三个月的使用也建议减少PTB的风险.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 过早分娩 (PTB) 是一个重大的全球健康挑战,导致新生儿死亡率和长期发育问题.
- 孕产妇的营养是影响PTB风险的关键可修改因素,与肥胖,感染和环境暴露等其他因素一起.
研究的目的:
- 调查母亲通过饮食摄入的和以及补充剂的使用与早产风险之间的关联.
- 分析营养摄入时间 (怀孕前,怀孕期间) 对后代PTB风险的影响.
主要方法:
- 采用了一个嵌套病例控制研究设计,利用来自大量孕妇队列的数据.
- 怀孕期间进行了饮食访谈,以评估营养摄入量,使用后勤回归模型分析PTB风险.
- 限制立方线模型被用来检查营养摄入量和PTB之间的非线性关联.
主要成果:
- 怀孕第二季度低摄入量与增加PTB风险显著相关.
- 在第三个三个月内不使用补充剂以及在怀孕前和怀孕期间低摄入量也与更高的PTB风险有关.
- 在,和补充剂摄入之间观察到关于PTB风险的协同效应.
结论:
- 建议在怀孕第二个三个月期间增加摄入量,并在怀孕期间增加摄入量,以预防PTB.
- 在第三个三个月内加强补充剂的使用可能会进一步降低PTB风险.
- 结果可以为公共卫生政策和产前营养指南提供信息,以减轻PTB.
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