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通过BASIC,可以在人类T细胞中无选择地有效地输入大DNA

Kexin Wang1, Xiaorui Li1, Jin Li1

  • 1Frontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.

Molecular therapy : the journal of the American Society of Gene Therapy
|January 4, 2026
PubMed
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No abstract available in PubMed .

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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