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Updated: Jan 7, 2026

Subnanometer-resolution Structural Determination of Hemagglutinin from Cryo-electron Tomography of Influenza Viruses

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Published on: November 7, 2025

流感A病毒血素亚型H15的抗原性结构和功能表征

Disha Bhavsar¹, André Nicolás León², Wei-Li Hsu³

¹Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA.

|January 4, 2026

概括

No abstract available in PubMed .

关键词:

CP:免疫学 H15 其他抗原漂移鸟类流感血凝素结构性病毒学

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Leaky Scanning

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...