在糖尿病视网膜病变中,PPARα 缺陷通过内皮衰老诱导血管病变
Leimeng Xu1, Rui Cheng2, Kelu Zhou2
1Department of Biochemistry and Physiology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
The American journal of pathology
|January 4, 2026
概括
No abstract available in PubMed .
相关概念视频
01:30Peripheral Artery Disease I: Introduction
285
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
285
01:20Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K