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Updated: May 5, 2026

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性酸酶触发电荷转换脂质纳米颗粒:一种用于口服核酸输送的创新方法

Ilaria Polidori1, Leonie Iris Weber2, Stefan Keim1

  • 1Department of Pharmaceutical Technology, University of Innsbruck, Institute of Pharmacy, Center for Chemistry and Biomedicine, 6020 Innsbruck, Austria.

International journal of pharmaceutics
|January 4, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
性酸酶基因治疗BASP1细胞透电荷转换在口服中

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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