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在口腔状细胞癌中对表观基因组进行DNA甲基化分析

Jun Ma1, Yu Huang2,3, Yuxin Bai4,1

  • 1Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun, 130021, People's Republic of China.

Human genomics
|January 4, 2026
PubMed
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No abstract available in PubMed .

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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