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Updated: Jan 7, 2026

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Jie Chen1, Yan Li2, Xue Bing2

  • 1Jining Medical University, Jining, Shandong, China.

Frontiers in medicine
|January 5, 2026
PubMed
概括

No abstract available in PubMed .

关键词:
TERT促进子突变乳腺癌病例报告纤维瘤样转移性癌症发生转移

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Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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