用于研究瘤微环境对电离辐射的反应的人体3D器官芯片培养平台

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Updated: May 4, 2026

Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing

Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing

Published on: June 9, 2016

Jerome Lacombe^1,2, Sean E Dunn¹, Marie Layac^1,3

¹Center for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ 85004, USA.

|January 5, 2026

概括

No abstract available in PubMed .

关键词:

生物技术癌症系统生物学细胞生物学免疫学

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Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...