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Updated: Jan 13, 2026

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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取决于DNA损伤的异形切换调节RIF1 DNA修复复合体组装和相位分离

Adenine Si-Hui Koo1, Weiyan Jia1, Sang Hwa Kim1

  • 1Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.

The Journal of biological chemistry
|January 6, 2026
PubMed
概括

RAP1交互因子1 (RIF1) 替代拼接产生不同的RIF1异型 (RIF1-L和RIF1-S),使其在DNA修复和基因组保护中的作用多样化. DNA损伤促进RIF1-S,影响蛋白质功能.

关键词:
造成的DNA损伤是DNA损伤.在MDC1中,MDC1是MDC1.在 RIF1 中, RIF1 是 RIF1 的一个类型.这是一种RNA结合蛋白.替代性拼接是一种替代性的拼接.细胞信号传递是细胞的信号传递.在这种情况下,染色染色素

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