美国的健康和儿科长期COVID的社会决定因素
Kyung E Rhee1, Tanayott Thaweethai2,3, Deepti B Pant2
1Department of Pediatrics, Division of Child and Community Health, University of California San Diego School of Medicine, Rady Children's Hospital, San Diego.
JAMA pediatrics
|January 6, 2026
概括
健康的不利社会决定因素,包括粮食不安全和社会环境不佳的经济不稳定,增加了儿科长期COVID的风险. 解决这些因素可能有助于减少儿童长期COVID的发病率.
科学领域:
- 儿科健康 儿科健康
- 流行病学 流行病学
- 健康的社会决定因素
背景情况:
- 全球数百万儿童患有SARS-CoV-2感染后的长期症状,对社会风险因素的理解有限.
- 假设健康的不利社会决定因素 (SDOH) 在儿童长期COVID的发展中发挥作用,因为它们对儿童环境的影响.
研究的目的:
- 研究美国学龄儿童和青少年中不良SDOH和长期COVID的几率增加之间的关联.
主要方法:
- 一项涉及52个美国地点的多中心,纵向元队列研究的横截面分析.
- 包括有学龄儿童 (6-11岁) 和有SARS-CoV-2感染史的青少年 (12-17岁).
- 在5个健康人2030 SDOH领域 (经济稳定,社会/社区环境,照顾者教育,社区,医疗保健准入) 中利用了潜伏类,用于回归建模.
主要成果:
- 经济不稳定,特别是与粮食不安全相结合时,与儿科长期COVID的几率增加显著相关 (aORs从1.57到2.39不等).
- 糟糕的社会和社区环境,包括高歧视和低社会支持,也显示出与长期COVID的更高几率的显著关联 (aOR, 2.17).
- 没有粮食不安全的经济不稳定与长期COVID的几率增加没有显著关联.
结论:
- 经济不稳定 (尤其是粮食不安全) 和不良的社会/社区环境与患儿长期COVID的可能性更高有关.
- 尽管存在其他经济挑战,但粮食安全似乎可以减轻长期COVID的风险.
- 需要进一步的研究来探索针对SDOH的干预措施,以潜在地降低儿科长期COVID发病率.
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