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针对TNFR2的生物药物:分子作用模式,可能的应用和未来的发展

Olena Zaitseva1, Harald Wajant1

  • 1Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

Journal of leukocyte biology
|January 6, 2026
PubMed
概括

瘤坏死因子-α (TNF) 阻断剂可以通过抑制有益的TNFR2活性在自身免疫性疾病中失败. 选择性TNFR2生物药物通过向自身免疫和癌症中的特定途径,提供了一个有前途的治疗策略.

关键词:
抗体是对抗体的重要组成部分.纳米体是一种纳米体.监管性T细胞 (Treg) 的使用瘤亡因子 (TNF) 受体-2 (TNFR2) 的发生.

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