根据年龄调整的D-Dimer截止值,以排除深静脉血栓
在PubMed上查看摘要
概括
此摘要是机器生成的。在怀疑腿部DVT的患者中,根据年龄调整的D-二次隔离值可以安全排除深静脉血栓症 (DVT). 这种方法增加了可以有效排除DVT的患者数量,尤其是老年人.
科学领域
- 血管医学
- 诊断成像
- 临床病理学
背景情况
- 对于诊断深静脉血栓症 (DVT) 的常规D-二次切断具有局限性,特别是在老年人中.
- 根据年龄调整的D-二次隔离剂在增加肺栓塞的诊断产量方面表现有希望,但需要对腿部DVT进行验证.
研究的目的
- 为了前性验证年龄调整的D-二次离子切断的安全性和有效性,排除疑似腿部深静脉血栓 (DVT).
主要方法
- 一项多中心,多国前性研究,涉及3205名涉嫌DVT的门诊患者.
- 患者使用威尔斯分数,敏感的D-二次测试和腿部超声波进行了评估.
- 患者被追踪3个月,以监测静脉血栓事件.
主要成果
- 患者的D- 二次元水平在500μg/ L和年龄调整的截止值之间没有发生DVT诊断失败.
- 在75岁及以上的患者中,年龄调整后的截止值使得D-二分体检测结果的负比从8. 7%增加到26. 1%,没有虚假阴性.
- 根据年龄调整的切断允许更多患者安全排除DVT.
结论
- 在怀疑腿部DVT的患者中,对年龄调整的D- 度量切断是排除深静脉血栓 (DVT) 的安全和有效工具.
- 这种方法提高了诊断效率,增加了可以自信地排除患有DVT的患者数量,特别是在老年人群中.
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