缓慢的步行速度和2型糖尿病中心血管事件的风险:系统性审查
Richard Baskerville1, Fiona Reid2, Pippa Oakeshott3
1Health and Life Sciences, Oxford Brookes University, Oxford, UK rbaskerville@brookes.ac.uk.
BJGP open
|January 6, 2026
概括
慢步速度与2型糖尿病 (T2DM) 患者心血管疾病 (CVD) 风险较高有关. 这一系统性审查证实了这种关联,突出了T2DM患者心血管疾病事件的关键指标.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是2型糖尿病 (T2DM) 患者的主要死亡原因.
- 评估心血管疾病风险对于T2DM患者的常规护理至关重要.
- 缓慢的步行速度是一般人群中心血管疾病事件的已知预测因素.
研究的目的:
- 研究步行速度和心血管事件之间的关联,特别是在2型糖尿病患者中.
- 确定慢步速度与心血管疾病风险之间的已确定的联系是否延伸到T2DM人群.
主要方法:
- 对涉及2型糖尿病患者的研究进行系统审查.
- 搜索了多个数据库 (PubMed Central, Web of Science, Cochrane, Google Scholar) 记录步行速度和随后的心血管疾病事件的研究.
- 包括四项高质量的研究,包括来自美国,英国和日本的132,967名参与者,使用纽卡斯尔-太华尺度进行评估.
主要成果:
- 四项研究符合纳入标准,涉及超过132,000名T2DM患者.
- 随访时间从3年到14年不等.
- 所有研究都报告了慢慢步行速度和致命和非致命心血管事件的风险增加之间存在显著的关联 (危险比1.18-5.88).
结论:
- 这一系统性审查提供了第一个证据,将步行速度降低与2型糖尿病中心血管疾病发病率增加联系起来.
- 慢步速度与较高心血管疾病风险之间的关联在T2DM患者的不同人群和环境中是一致的.
- 需要进一步的研究来探索潜在的干预措施,例如增加步行速度,以减轻T2DM中心血管疾病风险.
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