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重复测量的运动行为与学龄儿童的肥胖度之间的性别特定的纵向关联:一个组成数据分析方法
Natarajan Padmapriya1,2,3, Suresh Anand Sadananthan4, Navin Michael4
1Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. obgnp@nus.edu.sg.
International journal of obesity (2005)
|January 6, 2026
概括
儿童肥胖症受到运动行为,如体力活动和睡眠的影响. 这项研究发现了性别特异性联系,中度至强度的体力活动 (MVPA) 对女孩有益,睡眠对男孩有益,突出了对性别敏感干预的需要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 儿童肥胖研究儿童肥胖研究
- 在儿科的行为科学.
背景情况:
- 儿童肥胖症是一个日益关注的问题,受到运动行为的影响,如中度至剧烈的体力活动 (MVPA),光强体力活动 (LPA),久坐行为 (SB) 和睡眠.
- 这些24小时运动行为对肥胖的集体影响和性别特异性在儿童中仍未得到充分研究.
研究的目的:
- 调查儿童24小时运动行为和肥胖指标 (BMI,腹部肥胖) 之间的性别特异纵向关联.
- 以性别特定的方式探索替换不同的运动行为对肥胖结果的影响.
主要方法:
- 在GUSTO队列中的纵向研究,涉及使用加速度计重复测量24小时运动行为.
- 在多个时间点 (年龄为5.5-10.5岁) 通过BMI,腹周和MRI衍生的腹部脂肪体积来评估肥胖.
- 采用了组合的多变量线性混合效应建模和同位时间替代分析.
主要成果:
- 在所有肥胖结果中观察到显著的性别特异性相互作用.
- 在女孩中,较高的MVPA与较低的BMI和腹部脂肪度有关.
- 在男孩中,更长的睡眠时间与较低的BMI和腹部脂肪度相关. 用MVPA取代LPA/SB可降低两性肥胖,而用睡眠取代LPA/SB只对男孩有好处,特别是在内脏肥胖方面.
结论:
- 运动行为表现出与儿童肥胖的明显的性别特异关联,MRI衍生的测量显示出更强的相关性.
- 用MVPA替代轻度体力活动或久坐行为有效地降低了男孩和女孩的BMI和腹部脂肪.
- 替代睡眠对肥胖的益处仅在男孩身上明显,这强调了需要针对性别量身定制的生活方式干预措施来管理儿童肥胖症的需要.
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