基于深度学习的 Meniere 疾病的严重程度分级使用 2D MRI
Zheng Wang1, Yang Xue1, Yongjia Chen2,3
1School of Computer Science, Hunan First Normal University, Changsha, China.
Medical physics
|January 6, 2026
概括
一个新的深度学习系统,多阶段严重性评估系统 (MSAS),准确地划分和评分Meniere的细分和等级.
科学领域:
- 医学成像分析 医学成像分析
- 医疗保健中的深度学习
- 内耳疾病 内耳疾病
背景情况:
- 梅尼尔氏病 (Meniere's disease,简称MD) 是一种令人衰弱的内耳疾病,难以确诊.
- 目前MD的诊断方法缺乏准确性和一致性.
- 需要先进的深度学习细分工具来进行可靠的MD评估.
研究的目的:
- 开发和评估多阶段严重性评估系统 (MSAS).
- MSAS是一个深度学习框架,用于MD的精确细分和严重程度分层.
- 使用二维磁共振成像 (MRI) 来评估梅尼尔氏病.
主要方法:
- 在189名患者的MRI扫描 (开发) 上使用像素级手动细分开发的MSAS,并在70名患者 (外部测试组) 上验证.
- 集成的序列级预测和切片级细分,使用包括YOLO-V5和Grad-CAM在内的技术.
- 通过交叉与结合 (IoU),子系数,精度,平均平均精度 (mAP) 和曲线下的面积 (AUC) 来评估性能.
主要成果:
- MSAS实现了高的整体精度 (0.971) 和AUC (0.995).
- 显示出强烈的前庭区域检测 (mAP 0.887内部,0.877外部) 和细分 (子0.940内部,0.941外部).
- 切片注意力图和Grad-CAM为临床决策提供了更好的解释性.
结论:
- 深度学习技术显示出改善Meniere疾病诊断和严重程度分级的巨大潜力.
- 在MD管理中,MSAS框架提供了实质性的临床实用性.
- 这项研究通过先进的成像分析,促进了对梅尼耶氏病病理生理学的理解.
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