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Updated: Jan 13, 2026

Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems
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Published on: October 14, 2025

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菌体关联的Cas12p核酶需要与细菌雷多克辛结合,以激活和裂解点DNA

Zhipeng Wang1, Yujue Wang1, Hui Gao1

  • 1School of Physical Science and Technology and State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China.

Nature microbiology
|January 6, 2026
PubMed
概括

菌体利用细菌的硫素 (TrxA) 激活它们的Cas12p核酶,增强基因组降解. 这种意想不到的菌-细菌相互作用提高了对抗竞争菌的CRISPR免疫力.

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