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Updated: May 3, 2026

Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies
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血清PLA2R-IgG4/PLA2R-IgG比率动态揭示了在PLA2R相关的膜性脏病发病的进展过程中发生的致病性自身抗体亚类切换

Yongzhong Zhong1,2, Yunyun Liu3, Dan Zhou1

  • 1National Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Annals of medicine
|January 6, 2026
PubMed
概括

在膜性病 (MN) 中,自身抗体子类的切换并未得到充分理解. 这项研究表明,PLA2R-IgG4/PLA2R-IgG比率随着MN进展而增加,在后期阶段从IgG1/IgG3转向IgG4的主导地位.

关键词:
下一类 开关 开关子类反PLA2R抗体的抗体.膜性脏病是一种脏病.

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
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