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在血液透析患者中二次性甲状腺功能障碍的负担:一个横截面研究
Muhammad Ikram1, Hayat Ullah1, Muhammad Ayaz1
1Department of Nephrology, Lady Reading Hospital Medical Teaching Institution, Peshawar, PAK.
Cureus
|January 6, 2026
概括
二次性偏甲状腺症 (SHPT) 影响了近五分之一的血液透析患者. 在男性,糖尿病患者,高血压患者和长期透析患者中发现了较高的SHPT患病率,这强调了监测的必要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 二次性偏甲状腺症 (SHPT) 是血液透析的末期病 (ESRD) 患者的常见并发症.
- 由于功能障碍,SHPT是由,酸盐和维生素D的代谢障碍引起的.
研究的目的:
- 为了确定在依赖血液透析的ESRD患者中SHPT的频率.
- 在Khyber Pakhtunkhwa的一家三级护理医院进行的研究.
主要方法:
- 对127名血液透析患者 (年龄18至75岁) 的横截面研究,这些患者接受透析至少六个月.
- 由病定义的SHPT:改善全球结果 (KDIGO) 2017年指导方针 (完整的副甲状腺激素>9x上限).
- 根据年龄分层,透析持续时间,糖尿病和高血压分析数据.
主要成果:
- 在127名患者中,25名患者 (19.7%) 发现了SHPT.
- 在男性,透析持续时间较长的患者以及糖尿病和高血压同时存在的患者中观察到更高的SHPT频率.
- 平均年龄51.8±15岁;男性60.6%,糖尿病55.1%,高血压65.4%.
结论:
- 近五分之一的血液透析患者患有SHPT.
- 在男性,糖尿病患者,高血压患者和长期透析患者中,患病率更高.
- 强调定期的生化监测和早期干预,以获得更好的结果.
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