由Burkholderia cepacia引起的胆管败血症:一种罕见的呈现
Lee Matthew L Ponce1, Gelza Mae A Zabat1
1Infectious Disease, St. Luke's Medical Center, Quezon City, PHL.
Cureus
|January 6, 2026
概括
Burkholderia cepacia通常会引起肺炎,在免疫功能低下的患者中可能导致罕见的胆道感染. 这一案例凸显了需要考虑B. cepacia在高危人群的医院内胆道炎.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- Burkholderia cepacia通常会在免疫受损的个体中引起医院肺炎.
- 由于B. cepacia的肺外感染并不常见.
- 该患者患有肺腺癌,肝脏和脊柱转移,呈现出阻塞性黄.
研究的目的:
- 报告一种罕见的B. cepacia病例,导致医院胆道感染.
- 强调在免疫功能低下,患有无法解释的胆管炎的患者中考虑B. cepacia的重要性.
主要方法:
- 一名患有阻塞性黄的患者接受了内镜逆行胆血管细胞造影 (ERCP) 并插入支架.
- 手术后,患者发烧,并接受了胆管炎治疗.
- 血液和胆汁培养物确定了B. cepacia,导致抗生素调整和皮肤透肝胆汁排水.
主要成果:
- B. cepacia从血液和胆汁培养物中分离出来.
- 最初的抗生素治疗是无效的,但美罗和勒沃素的联合疗法导致了临床改善和负面的后续培养.
- 患者在接受口服levofloxacin的稳定状态下出院.
结论:
- 伯克霍德里亚 (Burkholderia cepacia) 可能是 nosocomial 胆道感染的致病原体.
- 免疫功能低下的患有胆管炎的患者应对B. cepacia进行评估.
- 及时和适当的抗生素治疗对于管理B. cepacia胆道感染至关重要.
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