对重症儿童进行修改的基于体积的食方案的可行性和安全性:试点研究
María José Solana García1,2,3,4, Jorge López González1,3,4, Gema Manrique Martín1,3,4
1Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Journal of pediatric gastroenterology and nutrition
|January 6, 2026
概括
对重症儿童来说,修改的基于体积的养实践 (MVBFP) 是可行的和安全的,尽管有肠道营养中断,但确保足够的营养. 这种方法可以改善卡路里和蛋白质的摄入,而不会产生不良影响.
科学领域:
- 儿科重症监护 儿科重症监护 儿科重症监护
- 临床营养学 临床营养学
- 医疗干预 医学干预
背景情况:
- 肠道营养中断 (ENI) 在重症儿童中很常见,往往导致营养不良.
- 基于体积的养实践 (VBFPs) 可以减轻ENI,但在儿科重症监护中缺乏报告.
研究的目的:
- 评估修改后VBFP (MVBFP) 在重症儿童的可行性和安全性.
- 评估24小时的补偿养是否可以有效地管理ENI.
主要方法:
- 一项前性纵向研究,涉及重病儿童 (1个月-18岁) 接受肠道营养.
- 实施MVBFP,以补偿性增加肠道养目标率 (CIEFGR) 来取代24小时内丢失的量.
- 数据收集包括人口统计,ENI细节,补偿养参数,摄入量和不良事件.
主要成果:
- 在21名儿童中发生了28次CIEFGR事件,平均补偿期为24小时.
- 在热量 (18.8 kcal/kg) 和蛋白质 (0.5 g/kg) 输送中实现了显著的增加.
- 轻微的胃肠道症状发生在10.7%的发作中,不需要干预;没有观察到显著的代谢变化.
结论:
- 使用补偿养的修改VBFP是一种可行且安全的策略,适用于重症儿童.
- 这种方法有效地改善了卡路里和蛋白质的供应,减轻了ENI造成的营养不良风险.
- 在这个人群中,MVBFP策略似乎没有增加胃肠道副作用.
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