在患有良性前列腺阻塞后的膀结石的患者中,囊托拉帕克西是否足够?
Mert Hamza Özbilen1, Mahmut Can Karabacak2, Taylan Tığlı2
1Department of Urology, Adana City Training and Research Hospital, Health Sciences University, Adana, Turkey.
The Prostate
|January 6, 2026
概括
在良性前列腺阻塞后的膀结石中,囊性托拉帕克西往往可以避免重复手术. 术前的指标,如尿液流量低和PSA高,表明二次干预的风险更高.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术创新 在外科创新.
- 患者的治疗结果.
背景情况:
- 良性前列腺阻塞 (BPO) 可以导致膀结石 (BS).
- 质疑BS与cystolitholapaxy同时进行BPO干预的必要性.
- 二次干预的预测者需要调查.
研究的目的:
- 评估在BS. cystolitholapaxy期间同时进行BPO手术的需要.
- 为了确定预测二次干预后cystolitholapaxy.的要求的因素.
主要方法:
- 一组由235名40岁以上的男性患者组成的BPO继发的BS队列接受了cystolitholapaxy.
- 随访时间超过12个月.
- 根据对二次干预的需要,患者被分类.
主要成果:
- 在平均49个月的随访后,19.5%的患者需要二次干预.
- 较低的峰值尿流率 (Qmax),较高的余空后体积 (PVR),较高的国际前列腺症状评分 (IPSS) 和较高的前列腺特异性抗原 (PSA) 与二次干预有关.
- 多变量分析证实低Qmax,高PVR,高IPSS和高PSA是重要的预测因素.
结论:
- 单独的囊性托拉帕克西通常是足够的,最大限度地减少了对额外手术的需求.
- 在手术前确定低Qmax,高PVR,高IPSS和高PSA可以指导同时进行BPO手术的决定.
- 结合这些预测因素的以患者为中心的方法可以优化治疗计划.
相关概念视频
01:25Urinary Tract Calculi VI: Surgical Management
366
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
366
01:30Urinary Tract Calculi III: Medical Management
191
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
191
01:28Urologic Endoscopic Procedure: Cystoscopic Examination
2.2K
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
2.2K
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
363
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
363
01:28Urinary Tract Calculi V: Nursing Management
262
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
262
01:27Urinary Tract Calculi IV: Nutrition Therapy and Prevention
348
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
348