在韩国国家肺癌查计划中S修饰物的流行,同时发生和预后影响
Hyungjin Kim1, Eunseo Jo2, Jinseob Kim2
1Department of Radiology, Seoul National University Hospital and College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea.
Radiology
|January 6, 2026
概括
针对肺癌查中偶然发现的结构化报告发现了显著的异常. 这些S调剂,包括冠状动脉化和肺气,与死亡风险增加有关.
科学领域:
- 放射学 放射学是指放射学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 在低剂量CT肺癌查期间,放射科医生对临床显著的偶然发现 (S修饰者) 的文档存在变化.
- 韩国国家肺癌查计划为七个标准化S调整剂实施了结构化报告,但它们的预后价值需要全面评估.
研究的目的:
- 通过分析它们的流行率,与死亡率的关联以及同时发生的模式,评估对S变异因子的结构化报告的实施.
- 验证标准化S调整剂在识别显著异常时的临床实用性.
主要方法:
- 在韩国国家肺癌查计划 (2019年8月至2020年12月) 中对基线查参与者的回顾性分析.
- 计算七个S修饰者的流行率.
- 用多变量考克斯回归评估所有原因死亡率的预后值.
- 隐性类分析 (LCA) 以确定并发模式和分层死亡风险.
主要成果:
- 在125,600名参与者中,2.69%的参与者经历了所有原因的死亡,平均随访时间为3.7年.
- 患病率:冠状动脉化 (15.07%),肺 (13.77%),间歇性肺异常 (ILAs) (2.65%),肺部感染 (0.90%).
- 所有S修饰剂都与全因死亡率的增加有关,危险比率从肺气的1.15到肺和/或心周输液的8.28不等.
- LCA确定了四个类别的死亡风险增加,从孤立的肺气到高风险的修饰剂.
结论:
- 在全国肺癌查队列中对七种标准化S调整剂进行结构化报告,证明了它们的流行率和与全因死亡率的关联.
- 这些发现验证了这些S调整剂在识别显著异常和分层死亡风险方面的临床实用性.
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